Category: daratumumab

Darzalex schedule change

I recently had a change in my dara schedule. I had been going once every 4 weeks, prior to this month. My doctor decided to have me go every 2 weeks, starting this month (April, 2019). He wanted to give that a try because of an increase in k/l ratio.

I still have a pretty low level of disease, so we’ll see what the change in treatment frequency does.

ComponentYour ValueStandard Range
Free Kappa5.21 mg/L3.30 – 19.40 mg/L
FREE LAMBDA315.72 mg/L5.71 – 26.30 mg/L
KAPPA/LAMBDA RATIO0.02  0.26 – 1.65

Still on Darzalex

This is just a quick update.  I’m still on Darzalex, but am also taking 2 mg of Pomalyst (pom) 21 days a month.  I’m not taking dex at the moment.  I just get 20 mg of dex with each dara infusion. We’ll see how that goes.

For the last 3 or 4 months, I’ve been getting dara via rapid infusion.   That cuts down on a lot of chair time. It feels like I may be having some more pronounced side effects from the rapid infusion in the form of fatigue and a bit of just feeling yucky.  I asked my doctor if he’s heard others say they feel a little worse after the rapid infusion, and he said that seems to be the case with some people.

Anyway, I am still alive and am stable at this point.

dara = daratumumab
pom = pomalidomide