For the second week, I took my 40 mg of dex at night last night. It didn’t prevent me from sleeping at all last night. Last week I did have to take some xanax about 1:00 am on Tuesday morning to get to sleep. I’ll see how it goes tonight. The biggest problems I seem to have with dex is the indigestion, edema and the speedy feeling. I have to say though, that I get pretty crabby! The pulsed dex weekly is much easier to tolerate than the 4 days on/4 days off was.