On Sunday I drove a friend to Rocky Mount, NC to visit some friends. It was 2 hours each way, with a few hours in between. By the time I got home, my feet felt as though they were in flames and someone was beating on the soles with a hammer. From the knees down felt numb. This happens to me when I have to sit for too long. This is a result of treatment with thalidomide and Velcade. Luckily, the pain and discomfort goes away by the next morning and I’m left with the numbness in just my feet.
What is it that makes the PN so much worse while sitting?